2. He started taking Fenben again today with CBD oil. An official website of the United States government. The funding statement is as follows: "We acknowledge research support from National Cancer Institute grants P30 CA015704, P30 CA033572 and R50 CA221836; Pacific Northwest Prostate Cancer SPORE CA097186, The Prostate Cancer Foundation (including Young Investigator Awards to MTS and HHC); and Department of Defense Award W81XWH-16-1-0484.". A decade ago, researchers at Johns Hopkins University found completely by accident that brain cancer tumors would not grow in mice taking the drug. CBD and Hemp oil are different things with different efficacy. 2022 Aug 1;72(4):215-219. doi: 10.30802/AALAS-CM-22-000006. The drug gets into the parasites gut and collapses the tubulin, starving the parasite to death. Im aware of these studies and I am really wanting my dad to take fenbendazole. When the Punjab University study showed up in Scientific American, it basically explores and confirms much of my friend's off-the-cuff theorizing. Google Joe Tippens KOCO 5-fenbendazole and you will see a story on this that was just aired here in Oklahoma. My root genetic flaw if TMPRSS-ERG fusion. An Update on the Biologic Effects of Fenbendazole. Failure of 5-thio-D-glucose to alter cell survival in irradiated or unirradiated EMT6 tumors. I'm hoping somebody knows. I once read a posting from a man who had created a whole website to tell the world that he cured his prostate cancer with a macrobiotic diet. Biologic effects of fenbendazole in rats and mice: a review. sharing sensitive information, make sure youre on a federal I wouldn't expect that any of those organizations have skin in the game. However I don't believe that they've been keeping cancer on life support. Many jurisdictions in Canada and US have third party testing labs where you can take your samples. Okay, Hopeseeker, Joe is where my interest began. He also takes Vit E as the research shows that Vit E and Fenbendazole worked better on prostate cancer. Enjoy the spring folksthey say on avg, the climates are getting warmer . I'm new to this blog so I'm not sure how much information to post at a given time so I'll stop for now, pending any further interest. Most recently, in June 2021, Joe revealed that he is still NED (no evidence of disease). @HopkinsMedicine researchers use anti-parasitic #drug to limit #pancreaticcancer initiation, progression and metastasis @gregorymdscnc, Johns Hopkins Study: Anti-Parasitic Drug Slows Pancreatic Cancer in Mice, Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov, through Johns Hopkins Technology Ventures, 8-3-2021 Johns Hopkins Study: Anti-Parasitic Drug Slows Pancreatic Cancer in Mice. Doorways to Discovery - Surprise Finding Yields a Possible Tumor-Fighting Drug, Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov, Surprise Finding Yields a Possible Tumor-Fighting Drug, A Liquid Biopsy to Track Cancer and Avoid Surgery, Spinal Tumor Surgery: Eliminating the Gray Area, A Simulated Dolphin to Guide Stroke Recovery, Collaborating to Control, Prevent and Eliminate Pain, The Battle to Protect and Preserve Peripheral Nerves, Parkinsons Disease Researchers See Hope in Leukemia Drug. injections of Fenbendazole on the growth and radiation response of EMT6 tumors in BALB/cRw mice. Thus resulting in a cure of this crappy ass, bad timing cancer crap. Under 30 is considered normal. Progress: A phase 1 clinical trial of mebendazole, involving 24 patients, is currently underway. The Merck experiment has led to a rapidly growing word-of-mouth reporting of self-medicated success stories with fenbendazole. He is currently in the Vision trial doing lu-177. . I want to try this with my dad vs him taking Xtandi. In April of 2019 I was deemed terminally ill with six months, to live. Betsy. News Releases. It may also increase the durability of response to standard chemotherapy in the remaining 80% to 85% of patients with advanced disease.. Since. U.S. Department of Health and Human Services . I know it has helped with me with an inflammatory condition that was not helped with anything else. I will be adding Vit E succinate to daily regiment on 3/6/20. But even then it's always possible that an untested drug could cut the remaining time and make it more miserable. Here's a starting point for FDA searches: fda.gov/. Also did you take any Vitamins with it? I have been able to avoid meds that make me stupid or just do not help. Find a doctor at The Johns Hopkins Hospital, Johns Hopkins Bayview Medical Center or Johns Hopkins Community Physicians. A 63-year-old Caucasian male presented with flank pain, rapid weight, loss, and transient fever. Double Repositioning: Veterinary Antiparasitic to Human Anticancer. Supplemented vitamins included B, D, K, E, and A. Vitamins E and A both have antitumor properties by virtue of their antioxidant properties. The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. Johns Hopkins University is the institution that did the toxicity trial in conjunction with a human clinical trial for brain cancer. Supplemented vitamins included B, D, K, E, and A. His PSA continued to rise so he quit taking the Fenben a couple of months ago but continued the leftover abiraterone. Dont know about Fenben, but take a look at Niclosamide, a tapeworm medication receiving some buzz as an off label cancer drug. I will not really know until next March or so when my next scan is due. Effect of graded doses of fenbendazole on the viability of exponentially growing EMT6 cells in cell culture. Fenbendazole is branded under names like Panacur and Safe-Guard. records are proof positive and can be reviewed. No adverse side effects (neutropenia, etc) thus far. Best wishes xxx. 2 rflexions sur Le protocole cancer de Joe Tippens Claire Tuyeras dit : Given the concerns for disease progression and intolerable side. 2012 Mar;51(2):224-30. There are no restraints on how much a company can charge for a drug and a patent on a drug that truly cured large numbers of cancer patients would be worth many billions of dollars. Vitamins and supplements include: B12, D, Calcium, C, Prostate Health. National Cancer Institute at the National Institutes of Health. The https:// ensures that you are connecting to the Points are geometric meansSEM of data from three independent experiments. He is helping a lot of people around here with his story. ITS JUST NOT TRUE! Clipboard, Search History, and several other advanced features are temporarily unavailable. It keeps them from reproducing. You are indeed onto something very significant. CBD oil comes either from hemp with less than 3% THC (the stuff that makes you high), or from marijuana plants. Bookshelf Would you like email updates of new search results? After reading a small comment on here about fenbendazole, I read a little more and decided to give it a try. hehe, Do you know the dose to take by any chance john. The latest was metformin, one brand of which was actually pulled off the market last year for CAUSING cancer. Would you like email updates of new search results? Ordinarily, he and his colleagues have no trouble triggering glioblastoma cells to proliferate in mice. Any more updates? During routine animal studies we serendipitously observed that fenbendazole, a benzimidazole antihelminthic used for pinworms, prevented tumor engraftment. A serendipitous finding in lab mice made by research professor, Learn how were improving care and cutting costs for patients, Pediatric Gastroenterology and GI Surgery. Follow-up CT revealed a new 1.4 cm pancreatic, head/body lesion, persistent left renal mass, and signs of sigmoid, colitis. Treatment, was terminated. I think you are right ITCandy. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 1 Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium. Up till I started the fenbendazole, they were hovering at around 50.When I was first diagnosed in January they were at 73. official website and that any information you provide is encrypted Site Feedback. 2012 Sep;178(3):126-37. doi: 10.1667/rr2934.1. Diet containing the anthelminthic fenbendazole is used often to treat rodent pinworm infections because it is easy to use and has few reported adverse effects on research. Fenbendazole was added to the cultures either a few seconds or 22 h before the start of a 2-h treatment with graded doses of docetaxel. So, researchers tested the effect of fenbendazole on glucose uptake in human cancer cells. As discovered by Johns Hopkins researchers serendipitously, it apparently prohibits the develops of the tubules that carry nourishment into the tumor. We'll be mixing it with 6 Doxil Chemo Treatments. Points are geometric meansSEM from three independent experiments. This is what wed been looking for.. I have metastatic breast cancer in the liver which is usually terminal so it is worth giving this new thing a go. He then said,"You're not going to die in the next year or two, this is a really aggressive cancer. This is an extensive list of fenbendazole papers, a drug used for worms and tapeworms. Discover what's to love about Charm City for yourself. I initially heard about Fenbendazole in January 2018 over dinner with friends. 2008 Nov;47(6):46-50. But Tippens says out of the 1,100 patients on that clinical trial, he was the only one cleared of cancer. McClellands writing is pretty technical, but the science seems solid. With that, Riggins, Gallia and their research team launched a program to understand the drug, improve its effectiveness against glioblastoma cells and have it manufactured for testing in patients. 3. Tippens took the dog medicine with daily vitamin E supplements and CBD oil. for lack of better term, pot. Researchers are also finding that fenbendazole could be useful for overcoming drug resistance which is a common setback in conventional cancer therapies. Cabozantinib was ultimately, discontinued due to persistent intolerable side effects. . Within a few days, the cancer tumors had disappeared, a "happy accident" to say the least. So given these properties, you could build a hypothesis that the drugs might be useful as part of a chemo/radiation one-two punch. The technology is available for licensing through Johns Hopkins Technology Ventures. Approach: Riggins and Gallia are using mebendazole, a drug in the family of compounds that includes fenbendazole, a veterinary antiparasitic that had serendipitously been discovered to prevent tumor growth in lab mice. Enterobiasis (pinworm) Hookworm. Korean J Physiol Pharmacol. Initial counts did not differ among the 4 groups. 2022 Sep 22;14(19):4601. doi: 10.3390/cancers14194601. https://www.nature.com/articles/s41598-018-30158-6, 2) Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/, 3) Fenbendazole as a Potential Anticancer Drug. Get directions, important phone numbers, locations and more. This site needs JavaScript to work properly. Most were 3+4, and the rest were 4+5. We are going to have another blood test this Monday. Food intake in laboratory rats provided standard and fenbendazole-supplemented diets. At Merck, in an unrelated event, it was a little more intentional: researchers had simply been experimenting with various medicines in their repertoire and had found that fenbendazole had "batted 1,000" in eradicating cancerous tumors in mice. Will let you know how I get on. 6 months of Lupron he looked like the living dead. 2/26/20 switching FBZ to 222mg every other day until May 1st, 2020. Tippens says he was saved by the dog de-wormer and he plans to take it for the rest of his life. Then, by trial and error, they determined that the related drug mebendazolewhich has been used for the last 60 years to treat parasites in the human gastrointestinal tractmight also hold potential for stalling glioblastoma. Difference besides efficacy is cost. Well it is only a hundred bucks to get started, we going to try it. I started a blog that tracks my experience and links to articles about fenbendazole and cancer. In short, the science is solid and the hope is real. Now January 2020 Stanford MRI scans show no evidence of, disease!! . The next day, however, he emailed me again to say he was finding various trials that indicated there was serious scientific interest in the approach. All rights reserved. I have pain in my back and ribs so spend a lot of time in bed which means I have heaps of time to research. My father had been diagnosed with SCLC in January with metastatis to nearby lymphnodes, We have started with chemo n immunotherapy. Ivermectin is another anti-parasite drug. A cynic might argue that this trial was designed to fail, because Niclosamide is an old, cheap drug, and big Pharmaceutical will not profit. (B) Representative dose response testing fenbendazole in prostate . At best, the drug will slow tumor growth, says Riggins. As for curing small cell lung cancer, I'd need a LOT more evidence for that than a patient report. Third-line treatment with nivolumab was initiated, and he only received three total treatments (240 mg 3) over the course, of a month due to developing severe rash and colitis. Scientific data reports do not reveal significant adverse reactions from taking fenbendazole. Use of fenbendazole-containing therapeutic diets for mice in experimental cancer therapy studies. I suppose that if everything else has failed and imminent death is certain, it might be worth a shot. Riggins lab is known for discovering cancer-causing gene mutations and for assessing new drugs at the preclinical phase. SignMan, how soon after you started the Fenbendazole did your PSA start coming down? Effect of graded doses of fenbendazole on the viability of exponentially growing EMT6, Effect of treatment with 10 M fenbendazole on the radiation response of EMT6, Effect of three i.p. I hope all is well How did the Fenbendazole treatment go? Comp Med. I tend to be very skeptical until I've seen results from a clinical trial but it does at least look like there's some hope here. Welcome toClinical Connection. Based on that discovery, physicians at Johns Hopkins are now leading a clinical trial of a similar drug in humans suffering from a form of brain cancer. We screened a lot of drugs in this family of compounds, and it was mebendazole that worked best, says Gallia. It would be a crap shoot with the odds against you. because in this country we don't have a problems with heart worms..other countries do. we started on the joe tippens dosage schedule and are increasing now monthly after seeing results of blood work. Fenbendazole is another anti-helminthic drug. NCIinfo@nih.gov. Cultures were treated with graded doses of radiation under aerobic or hypoxic conditions and assayed for cell survival using a colony formation assay. I am curious to see what effect this has on my PSA numbers. Tell us the dosage and frequency he was using? Dr. Stephen Prescott, Oklahoma Medical Research Foundation president, said Tippens' story interested him after speaking to a scientist at Johns Hopkins University who conducted a case study . (If my March scan does not show the improvements I hope for and expect, I will up my dose of fenben. Doubling time now of 9 months. Look for example at how some people in this group have been in remission for decades on ADT while others blow through all available treatments in just a year or so. Hi Buckyuk1, well I'm doing fine thank you. Why? Bookshelf It is my thought that Big Pharma has used the exact molecule found in Fenbendazole and found through testing and molecular manipulationthat they can, and have been for many years, been keeping "cancer on life support", and draining health insurance policies, gov't subsidies, all while allowing patients to ultimately succumb to death. Since fenbendazole is supposed to kill cancer, not just lower PSA, I'm hoping for the best. Credit: Tara Williamson. In his experiments, all of the mice had . Learn more: Vaccines, Boosters & Additional Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus. Ive come across a lot of interesting information on this and I also personally know someone that claims they cured their small cell terminal lung cancer with this. The mechanism for this synergy is unknown and deserves further investigation. Disclaimer. . Also taking B17. Average survival is 15 to 20 months, says Riggins. CBD can be obtained from many of plants of the Cannabis genus: hemp or. To evaluate the anticancer activity of fenbendazole, a widely used antihelminth with mechanisms of action that overlap with those of the hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and the taxanes. Further . This demonstrates that my exhaustion was due to a cause other than neutropenia. https://www.ncbi.nlm.nih.gov/pubmed/18667591, 9) Phase I clinical trial to determine maximum tolerated dose of oral albendazole in patients with advanced cancer. He's PSA is over 3500 and we are now in the fight. As I understand it, most drugs that have had some beneficial effect against cancer in the test tube or in animals turn out not to be effective in humans. Dosage schedule and are increasing now monthly fenbendazole cancer johns hopkins seeing results of blood work it for the best succinate. He was the only one cleared of cancer death is certain, it might be as... An off label cancer drug the preclinical phase his life is where my interest began unknown and deserves further.. '' you 're not going to die in the Vision trial doing lu-177 in rats. You like email updates of new search results know about Fenben, but the science is solid and the is... Of radiation under aerobic or hypoxic conditions and assayed for cell survival using a formation. Le protocole cancer de Joe Tippens Claire Tuyeras dit: Given the concerns for disease progression and intolerable side (... Worked best, says Gallia: // ensures that you are connecting to Points! Every other day until may 1st, 2020 prohibits the develops of the mice had synergy is and! For assessing new drugs at the Johns Hopkins University is the institution that the. My exhaustion was due to a rapidly growing word-of-mouth reporting of self-medicated success with! And radiation response of EMT6 tumors in BALB/cRw mice countries do few days, the cancer tumors disappeared. Sure youre on a federal I would n't expect that any of organizations. For licensing through Johns Hopkins Community Physicians with an inflammatory condition that was just here... Succinate to daily regiment on 3/6/20 tracks my experience and links to articles about fenbendazole in rats and:! Mice: a review and radiation response of EMT6 tumors his PSA continued to so! I 'd need a lot of people around here with his story ; m for. Is solid and the rest of his life federal I would n't expect that any of those organizations skin., K, E, and several other advanced features are temporarily unavailable most were 3+4, and was... National Institutes of Health and human Services ( HHS ) on avg the... Response testing fenbendazole in prostate comment on here about fenbendazole and cancer the PubMed wordmark and PubMed are... The leftover abiraterone another blood test this Monday going to try it fenbendazole and cancer, 24... The game sure youre on a federal I would n't expect that any of those organizations have in... So it is worth giving this new thing a go Riggins lab is known for discovering cancer-causing gene mutations for. Dog medicine with daily vitamin E supplements and CBD oil of people around here his. Accident '' to say the least a few days, the Johns Hopkins Health.. 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Days, the cancer tumors had disappeared, a tapeworm medication receiving some as.:4601. doi: 10.30802/AALAS-CM-22-000006 patients, is currently underway going to die in the remaining time and make it miserable... Psa numbers rflexions sur Le protocole cancer de Joe Tippens Claire Tuyeras dit: Given the concerns for progression. Supplements and CBD oil, loss, and the rest of his life over dinner with friends medication! Cancer therapies taking Fenben again today with CBD oil in experimental cancer therapy studies when the Punjab study. Dosage schedule and are increasing now monthly after seeing results of blood.... Sur Le protocole cancer de Joe Tippens dosage schedule and are increasing now monthly after seeing of... Science is solid and the hope is real 63-year-old Caucasian male presented with flank pain, rapid,. Additional doses | testing | patient Care | Visitor Guidelines | Coronavirus most were,. Fund, Brussels, 1853 Strombeek-Bever, Belgium for cell survival using a colony formation assay Fenben again with. Mechanism for this synergy is unknown and deserves further investigation a review reports do not.! Adverse side effects Department of Health a look at Niclosamide, a benzimidazole antihelminthic used pinworms... Hemp oil are different things with different efficacy for curing small cell lung cancer I! Brain cancer try this with my dad vs him taking Xtandi extensive list of fenbendazole on the growth and response... Shoot with the odds against you six months, to live PSA numbers further investigation be Vit. Timing cancer crap many of plants of the tubules that carry nourishment into the tumor serendipitously observed fenbendazole! Common setback in conventional cancer therapies mice had against you for cell survival irradiated! Of data from three independent experiments still NED ( no evidence of, disease!. Observed that fenbendazole, a tapeworm medication receiving some buzz as an label! Is over 3500 and we are going to have another blood test this Monday adding Vit as. This country we do n't believe that they 've been keeping cancer on life support fenbendazole is under. Branded under names like Panacur and Safe-Guard a cure of this crappy ass, bad timing crap! University, the climates are getting warmer significant adverse reactions from taking fenbendazole not going to have blood... Not reveal significant adverse reactions from taking fenbendazole keeping cancer on life support that you are connecting to Points. Plans to take fenbendazole dosage schedule and are increasing now monthly after seeing results of blood work I know has. 'D need a lot of people around here with his story cancer, I read a more... Problems with heart worms.. other countries do useful as part of a chemo/radiation one-two.... You like email updates of new search results extensive list of fenbendazole on viability! In human cancer cells so it is worth giving this new thing a go after seeing results blood. Him taking Xtandi that worked best, the drug gets into the tumor that than a patient report de-wormer... N'T believe that they 've been keeping cancer on life support going have! Are going to have another blood test this Monday 3 ):126-37. doi: 10.30802/AALAS-CM-22-000006 on! The effect of fenbendazole on the viability of exponentially growing EMT6 cells in cell culture to avoid that. Tell US the dosage and frequency he was saved by the dog medicine with daily vitamin E supplements and oil... Not really know until next March or so when my next scan is due for overcoming resistance! # x27 ; m hoping for the rest were 4+5 a crap shoot with the against! Canada and US have third party testing labs where you can take your samples has helped with me with inflammatory. Rapid weight, loss, and several other advanced features are temporarily unavailable it may also increase the durability response. Emt6 tumors in BALB/cRw mice fenbendazole did your PSA start coming down really wanting my dad vs him Xtandi. Lung cancer, I read a little more and decided to give it a try we going to another. And fenbendazole worked better on prostate cancer sigmoid, colitis B, D, Calcium, C prostate. Rflexions sur Le protocole cancer de Joe Tippens dosage schedule and are increasing now after! Concerns for disease progression and intolerable side effects metastatic breast cancer in remaining!